This server takes a set of unaligned sequences in FASTA format,
then builds a multiple sequence alignment in CLUSTAL, PIR, or PO format.
If you'd also like to see a visualization of your alignment in PO-MSA representation, use the POAVIZ Online server instead.
Scoring Matrix: Blosum80
Input Sequence Format:
Output Alignment Format:
Input: Enter the input data in text format:
Or click here to Upload Input Data.
Then enter the name of the uploaded file:
Interpret all residues as amino acids:
Interpret all residues as nucleotides:
POA assumes residues in upper case are amino acids, and residues in lower case are nucleotides.
Show Only Sequences with Indices: (comma delimited list, i.e. 0,1,2,4,6)
Exclude Sequences with Indices: (comma delimited list, i.e. 0,1,2,4,6)
POA will filter the MSA output to include or exclude the indicated sequences.
Perform Heaviest Bundling:
POA will use the heaviest bundling algorithm to find one or more consensus sequences.
Threshold Value for Heaviest Bundling:
The percent identity threshold for assigning a sequence to a given consensus sequence.
Show Only Consensus Sequences in the Multiple Sequence Alignment:
Fuse Aligned Nodes with the Same Residue Label:
While building up the PO-MSA.
Data generated by POAVIZ and POA Online are deleted from the server each day at 3:00am Pacific Time.